Coiled-coil register transitions and coupling with the effector's inhibitory site enables high fold changes in blue light–regulated diguanylate cyclases

Please refer to https://doi.org/10.1016/j.jbc.2025.111020 for the main publication, describing molecular details of a two-stage activation mechanism in LOV-diguanylate cyclases that allows tight dark-state inhibition while enabling high enzymatic activities upon illumination, achieving fold changes exceeding 10,000-fold. 

This entry reflects the corresponding raw data files for individual figure panels in https://doi.org/10.1016/j.jbc.2025.111020

Details of formatting and included content can be found in the file "Data_comments.pdf"