Raw Data associated with the paper: 'Homocysteine and cholesterol in the biomechanics and structural remodeling of the aorta during the development of atherosclerosis'

This data set contains mechanical and microstructural data on rabbit abdominal and thoracic aortas. The mechanical tests were performed using a biaxial tensile machine at the Institute of Biomechanics (Graz University of Technology). Histology was performed at the Department of Pathology (Medical University of Graz) and multi-photon microscopy at the Biomedical Center Core Facility Bioimaging (LMU Munich) using a Leica SP8 confocal microscope.

Regarding the mechanical analysis, this data set includes the statistical data (mean and experimental uncertainties) for each aortic region, treatment, and testing protocol used. In terms of microstructural investigation, the entire scans of the representative aortic wall sections shown in the paper are provided. 
Further information on methods used for the data collection can be found in the related publication: https://doi.org/10.1016/j.actbio.2026.05.039.

The data are organised into subfolders as follows:

• Histology
• Mechanics
• MPM
• ReadMe file featuring general information about the folder structure (ReadMe.txt)